Numerical study on spindle positioning using phase field method
نویسندگان
چکیده
منابع مشابه
Mechanisms of spindle positioning
Accurate positioning of spindles is essential for asymmetric mitotic and meiotic cell divisions that are crucial for animal development and oocyte maturation, respectively. The predominant model for spindle positioning, termed "cortical pulling," involves attachment of the microtubule-based motor cytoplasmic dynein to the cortex, where it exerts a pulling force on microtubules that extend from ...
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When a spindle is positioned asymmetrically in a dividing cell, the resulting daughter cells are unequal in size. Asymmetric spindle positioning is driven by regulated forces that can pull or push a spindle. The physical and molecular mechanisms that can position spindles asymmetrically have been studied in several systems, and some themes have begun to emerge from recent research. Recent work ...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2018
ISSN: 1478-3975
DOI: 10.1088/1478-3975/aaee45